pisaster

Ups, Downs.

I'm back from my travels to Friday Harbor Laboratories - my zoologist "home base" since 1996, though only my 6th stay at the labs. The original intent of the trip was a micro-sabbatical (UGA does not have real sabbaticals, unless you find external funding for it) to write, prepare for teaching in the fall, and put my feet amidst the Fucus and Balanus again at low tide, in a habitat I know less well than I'd like but better than almost any other.

My plans were interrupted. First, by good news - my work on Pisaster is recommended for NSF funding along with colleagues Mike Dawson, Lauren Schiebelhut, Ian Hewson, and Pete Raimondi. Fantastic news that required some scrambling to address a few issues before anything could be finalized, and of course made trickier by me not being at my office. So, good news for sure and you'll hear more about that in the coming few years.

Then, the very next day (still in my first week at the labs), terrible news. One of the most incredible undergraduate students I've yet interacted with, Katelyn Chandler, passed away unexpectedly. She was only 20. I worked with her first as a teacher in my "Monsters" class, and then for 3 semesters in the lab where she learned how to do qPCR, genotyping sea stars, and eventually her Honors thesis on differential expression among EF1A genotypes of Pisaster. She was incredibly intelligent, engaging, diligent, and creative, and will be very much missed by all of us in the Wares lab.

Below is a photo I took of her presenting the poster she made with almost no help (in terms of design, content, and so on), discussing science that she had done much of the creative and intellectual work on.

Katelyn will receive a posthumous degree from the University of Georgia; in only 2 years at UGA she had already amassed tremendous number of credits, had completed her Honors thesis, had coauthored a scientific publication, and had touched the lives of very many.

IMG_0834

Field and Stream of Consciousness

Good morning y'all. What a busy time summer is! Tomorrow I will head out to Skidaway Institute of Oceanography, one of the USG marine labs, to collect some Chthamalus for a project one of my undergraduates (Katie Skoczen) has started. I can't quit you, barnacles! And of course a nice little chance to drop by the beach before Memorial Day weekend too. After that, a short writing retreat and research prep trip to Friday Harbor Laboratories, my touchstone for my entire basis as a marine zoologist. Really looking forward to that!

I mention all this fun and hurry because we ARE all so busy. At some point it just feels good, maybe necessary, to call something "done". So I'm happy to also point to a new PeerJ PrePrint from the lab, work that my other fantastic undergraduate Katelyn Chandler has contributed to.

https://peerj.com/preprints/2990/

Fig3

Shown is Figure 3 from this manuscript. We think we are homing in on a story to tell about Pisaster and tolerance to Sea Star Wasting Disease! What this figure shows is changes in expression: individuals carrying the ins mutation on the left in each panel, individuals without on the right. All 3 panels tell the same story: the ins heterozygotes have dramatically lower expression of HUNDREDS of loci than homozygotes do. The first panel is all data; the second panel excludes one individual because it appears to be a funny recombinant (Katelyn's project for this Fall semester); and the third panel is focused on the elongation factor 1-alpha gene. You'll have to read the paper to know why all of this is so interesting!

As with some of my other papers, I have doubts about putting this paper at a "non-impact" journal like PeerJ, one that is focused through peer review on the correct analysis and interpretation rather than whether the story is sexy. Of course I think this story is sexy! But it has already been rejected without review from 2 journals, which reminds me (A) big data is not a big deal in an era of big data, and (B) all of the ego stroking of science often flows through a small handful of gatekeepers and reviewers. They may not be wrong, but lets remember they don't represent the ultimate impact of the science.

That, and the fact that I have very little funding to splurge on many of the more expensive OA journals (did you know Nature Communications costs $5200? Does that seem like those funds could be better used for science in an era of thin funding??? and yet that isn't Nature, it is another journal generated for the hunger of so many scientists needing to publish their work), and that I feel I can get this story out even if name recognition of the cover of the journal isn't as big for some of my colleagues, is why I continue to go with the good publishing experience at PeerJ.